Cancer Gene Therapy
"Interleukin-2 (IL-2) Gene Therapy with Allogeneic Fibroblasts in the CT-26 Model of Murine Colorectal Carcinoma."
Published in Gene Therapy Weekly, February 17th, 1997
According to the authors' abstract of an article published in Oncology Reports, "We previously demonstrated the efficacy of a genetically engineered vaccine composed of syngeneic tumor cells mixed with syngeneic, IL-2 gene transduced fibroblasts in the CT-26 model of murine colorectal carcinoma. In this report, we describe a more practical approach to fibroblast mediated IL-2 gene therapy that employs syngeneic tumor cells mixed with allogeneic, IL-2 gene transduced fibroblasts. BALB/c mice were challenged with an injection of CT-26, 14 days following immunization with IL-2 modified syngeneic BALB/c 3T3 (H-2(d)) or allogeneic C3H 3T3 (H-2(k)) fibroblasts mixed with irradiated CT-26. ...
Want to see the full article?
We're a pay-per-view site for premium content. If you'd like to purchase this article, it's only $3.00.
Welcome to NewsRx!
Learn more about a six-week, no-risk free trial of Gene Therapy Weekly
Source: Gene Therapy Weekly (1997-02-17)
More Articles from Gene Therapy Weekly
- Ribozyme Therapy
Hammerhead Ribozymes Exhibit Potential Gene Therapy Uses - Cancer Gene Therapy
FDA Clearance Received To Commence Phase I IL-2 Cancer Trial - Cancer Gene Therapy
Targeting of Melanoma Cells Possible with Recombinant Adenoviruses - Animal Models
Human Antibody Genes Introduced Into Antibody-Producing Mouse Strain - Antisense Technology
Tumorigenesis Inhibited by Cytosine-DNA MeTase Antisense Therapy - Brain Cancer
Identification of Cancer Gene Announced - More from this issue of Gene Therapy Weekly
NewsRx is Social
Follow us on your favorite social network by clicking on a button below:
Top Medical Newsletters
Awards
Best Health/Healthcare Content, 2012
Best Health/Healthcare Content, 2011
Best e-Business Site, 2010
Best e-Business Site, 2009
Best e-Business Site, 2008
Best e-Business Site, 2007
Best e-Business Site, 2006
Best Healthcare Content, 2005
Best Overall Internet Site, 2005
Best Interactive Site, 2005
Facts & Stats
NewsRx also is available at LexisNexis, Gale, ProQuest, Factiva, Dialog, Thomson Reuters, NewsEdge, and Dow Jones.
- Google 2010 PageRank: #2 Among Top Health News and Media Publications
- Google 2010 PageRank: #2 Among Top Science Publications in Biology/Physiology
- Google 2010 PageRank: #2 Among Top News and Media for the Business of Pharmaceuticals
- Amazon's Alexa 2010 PageRank: #2 News and Media Site for the Pharmaceutical Industry
