Suicide Gene Therapy
"Bone Marrow Purging of Residual Breast Cancer by Adenoviral Transfer of the HSVtk Gene."
Published in Gene Therapy Weekly, February 17th, 1997
According to an abstract submitted by the authors to the 38th Annual Meeting of the American Society of Hematology, held December 6-10, 1996, in Orlando, Florida, "High dose chemotherapy with autologous bone marrow transplant support has become an important treatment for patients with breast cancer. A limitation of BMT, however, is the potential contamination of the autologous graft with residual tumor cells (MRD). We have created a MRD purging technique based on the ability of a recombinant adenoviral vector (ad-v) to efficiently infect breast cancer cells but not hematopoietic cells. We generated a recombinant ad-v carrying the bifunctional protein GAL-TEK which is an inframe fusion...
Want to see the full article?
We're a pay-per-view site for premium content. If you'd like to purchase this article, it's only $3.00.
Welcome to NewsRx!
Learn more about a six-week, no-risk free trial of Gene Therapy Weekly
Source: Gene Therapy Weekly (1997-02-17)
More Articles from Gene Therapy Weekly
- Ribozyme Therapy
Hammerhead Ribozymes Exhibit Potential Gene Therapy Uses - Cancer Gene Therapy
FDA Clearance Received To Commence Phase I IL-2 Cancer Trial - Cancer Gene Therapy
Targeting of Melanoma Cells Possible with Recombinant Adenoviruses - Animal Models
Human Antibody Genes Introduced Into Antibody-Producing Mouse Strain - Antisense Technology
Tumorigenesis Inhibited by Cytosine-DNA MeTase Antisense Therapy - Brain Cancer
Identification of Cancer Gene Announced - More from this issue of Gene Therapy Weekly
NewsRx is Social
Follow us on your favorite social network by clicking on a button below:
Top Medical Newsletters
Awards
Best Health/Healthcare Content, 2012
Best Health/Healthcare Content, 2011
Best e-Business Site, 2010
Best e-Business Site, 2009
Best e-Business Site, 2008
Best e-Business Site, 2007
Best e-Business Site, 2006
Best Healthcare Content, 2005
Best Overall Internet Site, 2005
Best Interactive Site, 2005
Facts & Stats
NewsRx also is available at LexisNexis, Gale, ProQuest, Factiva, Dialog, Thomson Reuters, NewsEdge, and Dow Jones.
- Google 2010 PageRank: #2 Among Top Health News and Media Publications
- Google 2010 PageRank: #2 Among Top Science Publications in Biology/Physiology
- Google 2010 PageRank: #2 Among Top News and Media for the Business of Pharmaceuticals
- Amazon's Alexa 2010 PageRank: #2 News and Media Site for the Pharmaceutical Industry
