Published in Gene Therapy Weekly, February 24th, 1997
Mechanisms leading to hematologic abnormalities in HIV-1 infection are unclear and may involve multiple factors, noted Aliette Marandin, Hopital St. Louis, Paris, France, and colleagues ("Loss of Primitive Hematopoietic Progenitors in Patients with Human Immunodeficiency Virus Infection," Blood, December 15, 1996;88:4568-4578).
Although cytopenia and morphologic bone marrow changes often are seen in HIV/AIDS patients, the mechanisms associated with these cytopenias are unknown. "... an attractive hypothesis to explain the...
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