Gene Therapy Weekly

Susan Hasty, Publisher

Table of Contents . . . March 3rd, 1997

Non-Subscriber - Summaries Only

Related Areas: Other Issues in Gene Therapy Weekly | Other Publications

Conference Coverage (Retrovirus) - New Approach Pits HIV Against Itself

Conference Coverage (Retrovirus) - PI-Resistant HIV Develops New Tricks

Cancer Gene Therapy - Cancer Induced Cachexia Prevented by IL-10 Gene Transfer

Colon Cancer - More Progress in Cancer Genetics

DNA Absorption - Food-Ingested Foreign DNA Survives the Gastrointestinal Tract

Gene Transfer Techniques - Human Dendritic Cells Susceptible to Genetic Engineering with Adenoviruses

Genetics - Association Analysis Finds Common Disease Genes

Genetics - Patent Announced on AGT Hypertension Gene Mutation

Genetics - Silicon Chips Scan Thousands of Genes at Once, Speeding Studies

Human Papillomavirus - Physicians Begin Testing First HPV Vaccine

Immunotherapy (Melanoma) - Vaccines Engineered to Secrete IL-2 or gammaIFN Show Anticancer Potential

Industry News (Acquisitions) - Gene Expression Technology Rights Acquired

Industry News (Joint Venture) - Collaboration Announced To Develop Class of CNS Compounds

Antisense Therapy (Breast Cancer) - "Antisense Down-Regulation of Metallothionein Induces Growth Arrest and Apoptosis in Human Breast Carcinoma Cells."

Cancer Gene Therapy - "Prolonged Survival of Mice Bearing Disseminated Gastric Cancer by Adenovirijs-Mediated Gene Therapy."

Cancer Gene Therapy - "Ribozyme-Mediated Inhibition of Human Telomerase Activity In Extracts of Hepatocellular Carcinoma Derived Lines."

Pathogenesis (HCV) - "Hepatitis C Virus-Specific Hammerhead Ribozymes Cleave Target RNA Efficiently and Inhibit Viral Gene Expression."

Pathogenesis (T. Cruzi) - "Identification of the 83-kDa Amastigote Surface Protein of Trypanosoma cruzi as a Member of the Sialidase Family and a Target of CTL Responses."

Suicide Gene Therapy - "Mechanism of Action of Thymidine Kinase Suicide Gene Therapy in a Transplantable Rat Mesothelioma."

Suicide Gene Therapy - "Retinoids Augment the Bystander Effect In HSVtk/GCV Mediated Gene Therapy By Enhanced Gap Junctional Intercellular Communication."

Antisense Technology - "Binding Affinity and Specificity of Escherichia coli RNase H1: Impact on the Kinetics of Catalysis of Antisense Oligonucleotide-RNA Hybrids."

Antisense Technology - "Improved Oligonucleotide Uptake and Stability by a New Drug Carrier, the SupraMolecular BioVector (SMBV)."

Antisense Technology - "Inhibition of Vesicular Stomatitis Virus in Cells Constitutively Expressing an Antisense RNA Targeted Against the Virus RNA Polymerase Gene."

Antisense Technology - "Mixed Backbone Antisense Oligonucleotides: Design, Biochemical and Biological Properties of Oligonucleotides Containing 2'-5'-ribo- and 3'-5 SINGLEQ

Antisense Technology - "Rapid Sequence-Independent Cellular Response to Oligodeoxynucleotides."

Cancer Gene Therapy - "In vitro Antigene Therapy Targeting HPV-16 E6 and E7 in Cervical Carcinoma."

Cardiology - "Physiological Effects of Adenoviral Gene Transfer of Sarcoplasmic Reticulum Calcium ATPase in Isolated Rat Myocytes."

Gene Delivery - "Cutaneous Gene Therapy."

HIV Gene Therapy - "In vitro Separation and Expansion of CD4 Lymphocytes from HIV-Infected Individuals Without Activation of HIV Infection."

Hammerhead Ribozymes - "Effects of Variations in Length of Hammerhead Ribozyme Antisense Arms upon the Cleavage of Longer RNA Substrates."

Hematology - "FLT3 Ligand Preserves the Ability of Human CD34⁺ Progenitors to Sustain Long-Term Hematopoiesis in Immune-Deficient Mice after ex vivo Retroviral-Mediated Transduction."

Immunogenetics - "IMGT, the International ImMunoGeneTics Database."

Immunology - "Induction of Antigen-Presenting Capacity in Tumor Cells upon Infection with Non-Replicating Recombinant Vaccinia Virus Encoding Murine MHC Class II and Costimulatory Molecules."

Liposomes - "Stabilization of Cationic Liposome-Plasmid DNA Complexes by Polyamines and poly(ethylene glycol)-Phospholipid Conjugates for Efficient in vivo Gene Delivery."

Liposomes - "Sterically Stabilized Ph-Sensitive Liposomes - Intracellular Delivery of Aqueous Contents and Prolonged Circulation in vivo."

Vascular Tissue - "The Dispatch(TM) Catheter as a Delivery Tool for Arterial Gene Transfer."

Vector Development - "Adenovirus-Mediated Inducible Gene Expression Through Tetracycline-Controllable Transactivator with Nuclear Localization Signal."

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