Gene Transfer Techniques

Human Dendritic Cells Susceptible to Genetic Engineering with Adenoviruses

Published in Gene Therapy Weekly, March 3rd, 1997

Genetic engineering of dendritic cells (DCs) to express tumor antigens is a potential anticancer therapeutic.

DCs are extremely potent antigen presenting cells (APCs). They have the capacity to acquire and process antigens, to migrate to lymphoid organs, and to stimulate antigen-specific T cells to proliferate. Only recently have methods been developed which make it possible to culture large numbers of DCs from the adherent fraction of peripheral blood mononuclear cells (PBMCs) (S.M. Kiertscher et al., J. Leukoc. Biol., 1996;59:208-18).

Jill F. Arthur and colleagues from the University of California hypothesized that genetic engineering of DCs to...

Want to see the full article?

Purchase this article for only $3.00

We're a pay-per-view site for premium content. If you'd like to purchase this article, it's only $3.00.

Welcome to NewsRx!

Learn more about a six-week, no-risk free trial of Gene Therapy Weekly

Source: Gene Therapy Weekly (1997-03-03)

NewsRx is Social

Top Medical Newsletters

Awards

Best Health/Healthcare Content, 2012
Best Health/Healthcare Content, 2011
Best e-Business Site, 2010
Best e-Business Site, 2009
Best e-Business Site, 2008
Best e-Business Site, 2007
Best e-Business Site, 2006
Best Healthcare Content, 2005
Best Overall Internet Site, 2005
Best Interactive Site, 2005

Facts & Stats

NewsRx also is available at LexisNexis, Gale, ProQuest, Factiva, Dialog, Thomson Reuters, NewsEdge, and Dow Jones.

Google 2010 PageRank: #2 Among Top Health News and Media Publications
Google 2010 PageRank: #2 Among Top Science Publications in Biology/Physiology
Google 2010 PageRank: #2 Among Top News and Media for the Business of Pharmaceuticals
Amazon's Alexa 2010 PageRank: #2 News and Media Site for the Pharmaceutical Industry