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Gene Therapy Weekly

Susan Hasty, Publisher

Table of Contents . . . March 17th, 1997

Non-Subscriber - Summaries Only

Related Areas: Other Issues in Gene Therapy Weekly | Other Publications

Antisense Technology - Suppression of SPARC Expression Decreases Melanoma Tumorigenicity

Antisense Technology - 2-5A Drug May Inhibit Respiratory Syncytial Virus in Infants

Cancer Gene Therapy - Adenovirus-Mediated Bcl-xS Transduction Enhances Apoptosis in Neuroblastoma

Cancer Gene Therapy - HIV-1 Vpr Tumor Suppressive Effects Reported

Cancer Gene Therapy - Onyx Begins Testing Anticancer Agent

Cancer Gene Therapy (GammaIFN) - Local and Systemic Results Obtained from Intralesional Vector Administration

Drug Delivery - Gene Expression Drug Delivery System Discoveries Announced

Genetics - License Completed for Gene-Activated Erythropoietin

Genetics - Monkey Cloning Procedure Aids Research and Fuels Controversy

HIV Gene Therapy - Clinical HIV Gene Therapy Trial Initiated: In Vitro Data Encouraging

HIV-Based Vectors - Pseudotyped, Defective, High-Titer HIV-1 Particles Show Potential

Hematology - Potential Control of GVHD via HSVtk/GCV Gene Therapy

Industry News (Joint Venture) - Collaboration Entered To Construct Genomic Libraries

Industry News (Joint Venture) - Licensing Agreement for Genomic Database Signed

Infertility - Researchers Find Genetic Link

Antisense Therapy (Malaria) - "Ribozymes as Antimalarials."

Entamoeba histolytica (Vaccine) - "Successful Immunization Using Serine-Rich Entamoeba Histolytica Protein Fused to Cholera Toxin B Subunit Expressed by Attenuated V. cholerae."

Gender Differences (Schistosoma) - "Evidence for an Androgen Receptor in Schistosoma mansoni and Alteration of Gene Expression in the Presence of Testosterone."

Genetic Analysis (HIV-1) - "Positive and Negative Sense Transcription from the HIV-1 LTR."

Genetics (Malaria) - "Production of the Monoclonal Anti-Plasmodium falciparum Liver-Stage Antibodies."

HIV Gene Therapy - "Gene Therapy in HIV."

Leishmaniasis (Vaccines) - "Recombinant Leishmanial Antigens in Vaccine Development."

Antisense Technology - "Antisense Oligonucleotide Inhibition of PDGFR-Beta Receptor Subunit Expression Directs Suppression of Intimal Thickening."

Antisense Technology - "Antisense Targeting of E6AP Elevates p53 in HPV-Infected Cells but Not in Normal Cells."

Antisense Technology - "In vitro Mutational and Inhibitory Analysis of the Cis-Acting Translational Elements Within the 5' Untranslated Region of Coxsackievirus B3: Potential Targets for Antiviral Action of Antisense Oligomers. DOUBL

Antisense Technology - "Inhibition of p75 Tumor Necrosis Factor Receptor by Antisense Oligonucleotides Increases Hypoxic Injury and Beta-Amyloid Toxicity in Human Neuronal Cell Line."

Antisense Technology - "On-Line HPLC Electrospray Mass Spectrometry of Phosphorothioate Oligonucleotide Metabolites."

Antisense Technology - "Selective Inhibition of Human and Mouse Natural Killer Tumor Recognition using Retroviral Antisense in Primary Natural Killer Cells - Involvement with MHC Class I Killer Cell Inhibitory Receptors."

Antisense Technology (Vascular Tissue) - "Intimal Hyperplasia Following Vascular Injury is Not Inhibited by an Antisense Thrombin Receptor Oligodeoxynucleotide."

Cancer Gene Therapy - "Complete Regression of Established Murine Hepatocellular Carcinoma by in vivo Tumor Necrosis Factor alpha Gene Transfer."

Cancer Gene Therapy - "IFN Regulatory Factor-1 Gene Transfer into an Aggressive, Nonimmunogenic Sarcoma Suppresses the Malignant Phenotype and Enhances Immunogenicity in Syngeneic Mice."

Cancer Gene Therapy - "In vivo Gene Therapy for alpha-Fetoprotein-Producing Hepatocellular Carcinoma by Adenovirus-Mediated Transfer of Cytosine Deaminase Gene."

Cancer Gene Therapy - "Nuclear Localization Signal Peptides for the Import of Plasmid DNA in Gene Therapy (Review)."

Cord Blood - "Murine Model for Human Cord Blood Transplantation: Near-Term Fetal and Neonatal Peripheral Blood Cells Can Achieve Long-Term Bone Marrow Engraftment in Sublethally Irradiated Adult Recipients."

Diabetes - "Targeted Expression of the Neuropeptide Calcitonin Gene-Related Peptide to beta Cells Prevents Diabetes in NOD Mice."

Gene Delivery - "Peptide-Mediated Gene Delivery: Influence of Peptide Structure on Gene Expression."

Kaposi's sarcoma - "Vascular Endothelial Growth Factor Vascular Permeability Factor Is an Autocrine Growth Factor for AIDS-Kaposi sarcoma."

Keratinocyte Gene Therapy - "In vivo Transfer of a Foreign Gene to Keratinocytes using the Hemagglutinating Virus of Japan Liposome Method."

Malaria Gene Therapy - "Single Immunizing Dose of Recombinant Adenovirus Efficiently Induces CD8+ Cell-Mediated Protective Immunity Against Malaria."

Neuroscience - "Cell Type-Specific Expression in Brain Cell Cultures from a Short Human Cytomegalovirus Major Immediate Early Promoter Depends on Whether It Is Inserted into Herpesvirus or Adenovirus Vector."

Neuroscience - "Lipofectin-Facilitated Transfer of Cholecystokinin Gene Corrects Behavioral Abnormalities of Rats with Audiogenic Seizures."

Parkinson's Disease - "Dopaminergic Neurons Protected from Degeneration by GDNF Gene Therapy."

Reproductive Biology - "Adenovirus-Mediated Gene Transfer to Rat Testis in vivo."

Transfection Efficiency - "Studies of DEAE-Dextran-Mediated Gene Transfer."

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