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Antisense Technology

2-5A Drug May Inhibit Respiratory Syncytial Virus in Infants

Published in Gene Therapy Weekly, March 17th, 1997

A drug based on 2-5A antisense technology from Atlantic Pharmaceuticals, Half Moon Bay, California, achieved up to 95 percent eradication rates of respiratory syncytial virus (RSV) in infected tissue culture.

RSV is the principle cause of lower respiratory infections such as pneumonia and brochiolitis in infants and children, and is responsible for at least 90,000 hospitalizations and 4,500 deaths in the United States each year.

The Cleveland Clinic, Ohio, conducted the study in collaboration with the U.S. National Institutes of Health (NIH). Gemini Technologies, Inc. is the exclusive licensee of the 2-5A antisense technology. Results of the study...

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