Published in Gene Therapy Weekly, March 24th, 1997
HSV-TK/GCV suicide gene therapy has been a useful tool and/or therapy in several areas of medical science. It has been used as a negative dominant selectable marker; used to study lineage formation in cultured cells and transgenic animals; used to achieve conditional ablation of targeted cell types; as a gene therapy to selectively treat tumor cells; and has also been studied as a method of controlling HIV infection.
Anthony Muyombwe and...
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