Cancer Gene Therapy
"Inhibition of Established Pancreatic Cancers Following Specific Active Immunotherapy with Interleukin-2 Gene-Transduced Tumor Cells."
Published in Gene Therapy Weekly, May 12th, 1997
According to the authors' abstract of an article published in Cancer Gene Therapy, "Pancreatic cancer has a poor prognosis even when complete resection can be accomplished. Recent studies have demonstrated that the immune system is capable of mounting effective tumor-specific immune responses even against 'nonimmunogenic' tumors. The studies reported herein were conducted to determine if induction of tumor-specific immune responses capable of inhibiting in vivo pancreatic tumor growth could be achieved through active immunization with pancreatic tumor cells genetically engineered to secrete interleukin-2 (IL-2). A relevant poorly immunogenic subcutaneous model of murine ductal...
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Source: Gene Therapy Weekly (1997-05-12)
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