Conference Coverage (AACR)

Antisense Therapy Under Development as Anticancer Therapeutic

Published in Gene Therapy Weekly, May 12th, 1997

University of Alabama researchers have been exploring the pharmacokinetics of second generation antisense oligonucleotides as anticancer therapeutics.

Ruiwen Zhang, an Assistant Professor at the Department of Pharmacology and Toxicology at the University of Alabama at Birmingham, Alabama, presented research results of work in this area to the American Association for Cancer Research conference, held April 12-16, 1997, in San Diego, California.

"Overexpression of the RI(alpha) subunit of type I protein kinase A (PKA) has been observed in human tumors, and the development of antisense oligonucleotides to inhibit PKA expression has been suggested to be...

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Source: Gene Therapy Weekly (1997-05-12)

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