AIDS Therapies
New Assay Speeds, Improves HIV Monitoring and Drug Testing
Published in Gene Therapy Weekly, May 12th, 1997
The assay may even lead to a way to test patients' infectious viral burden, perhaps yielding previously unavailable prognostic data.
Currently, HIV infectivity is monitored by assessing viral p24 antigen production or by HeLa-CD4 plaque assays. Both tests are time consuming and yield limited data.
Now University of California, San Diego researchers Alain Gervaix and colleagues report the development of a new assay: a CEM cell line containing a plasmid encoding the green fluorescent protein (humanized S65T GFP) driven by the HIV-1 long terminal...
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Source: Gene Therapy Weekly (1997-05-12)
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