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Chimpanzees Protected From HIV-1 Infection By New DNA Vaccine

Published in Gene Therapy Weekly, May 12th, 1997

Using an innovative DNA-based vaccine, a research team led by University of Pennsylvania Medical Center scientists has successfully protected chimpanzees against massive doses of HIV-1.

The vaccine's effectiveness is unprecedented in a primate species that, like humans, is susceptible to HIV-1 infection. A report of the team's findings appeared in the May 1997 issue of Nature Medicine.

The study represents significant progress in two important areas. First, it encourages hope that a human HIV-1 vaccine may prove possible in time, and, second, it shows that the genetic vaccine strategy -- now in clinical trials against herpes, influenza, certain...

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