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Glaucoma

Cause of Glaucoma May Be A Gene That Can Serve As A New Target For Drug Therapy

Published in Gene Therapy Weekly, May 26th, 1997

Most cases of glaucoma may be caused by a gene that becomes highly active in response to biological stress, researchers from the University of California San Francisco reported.

The origins of glaucoma, which affects three to four million people in the United States and blinds 12,000 of them each year, have long been a mystery, but new evidence that a gene and its encoded protein are involved raises hope that an understanding of the mechanisms of the disease is within reach, and also suggests new treatment possibilities.

Within the eye, sources of biological stress such as trauma or injury generate injurious forms of oxygen called "free radicals,"...

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