Alport Syndrome

Inherited Kidney Disorder Traced To Arrested Development Of Membranes

Published in Gene Therapy Weekly, June 2nd, 1997

Researchers at the University of Pennsylvania Medical Center report that arrested development in the kidney may lie at the center of the deadly disease known as Alport Syndrome.

In individuals with this inherited kidney disorder, a membrane crucial to the kidney's function steadily degrades, splitting and thinning until the vital organ fails.

The new findings were described in the May 15 issue of the Journal of Clinical Investigation, which features an image from the study on its cover.

The average human kidney faces daunting duty, filtering more than 70 liters of fluid each day through internal structures called glomerular...

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Source: Gene Therapy Weekly (1997-06-02)

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