"Protective Humoral Responses to the C-Terminus of MSP-1 from P. yoelli."

According to an abstract submitted by the authors to the Sixth Annual Meeting of the International Centers for Tropical Disease Research, National Institutes of Health, held May 5-7, 1997, in Bethesda, Maryland, "We have sought to identify in vitro correlates of immune responses which protect mice against malarial challenge infection. To do this, we have studied antisera generated against a vaccine candidate derived from the erythrocytic stages of plasmodial parasite development - the merozoite surface protein-1 (MSP-1). Previously, we have shown that immunization with a fusion protein containing the carboxyl-terminal epidermal growth factor-like (EGF-like) domains of MSP-1 from...

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