Published in Gene Therapy Weekly, June 30th, 1997
By far, the most effective AIDS vaccine prototype is a live simian immunodeficiency virus (SIV) vaccine attenuated by deletions in the nef, vpr, and LTR genes. The new findings may slow the growing support for human tests of a similarly attenuated live HIV vaccine.
"The importance of nef ... seems to be less than that implied by the finding of long-term survivors with spontaneous nef deletions or the absence of simian AIDS in monkeys infected with nef-deficient...
Want to see the full article?
Welcome to NewsRx!
Learn more about a six-week, no-risk free trial of Gene Therapy Weekly
NewsRx also is available at LexisNexis, Gale, ProQuest, Factiva, Dialog, Thomson Reuters, NewsEdge, and Dow Jones.