Published in Gene Therapy Weekly, July 7th, 1997
Because arthritis is an autoimmune disease wherein an antiinflammatory response has been activated, the local delivery of anti-inflammatory proteins may provide an effective treatment. Researchers have attempted ex vivo and in vivo approaches for delivery of therapeutic genes.
Unfortunately, the ex vivo approaches have been technical and time consuming, and the in vivo approaches have not been capable of transfecting the articular cartilage. Now, Tetsuya Tomita and colleagues from the Osaka University,...
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