Alzheimer's Disease

U.S. Scientists Pinpoint Role of Alzheimer's Genes

Published in Gene Therapy Weekly, September 22nd, 1997

A defect in the ability of a cell to properly parcel out its genetic material when it makes a copy of itself may be an underlying cause of most inherited cases of Alzheimer's disease, a new study suggests.

Five Harvard University researchers reported in the September 5, 1997, issue of the journal Cell that they have uncovered the tasks performed by two chunks of genetic material, known as presenilin 1 and presenilin 2. Those genes, which have been implicated in the familial form of Alzheimer's, help govern a cell's ability to make copies of its genetic material and send a complete copy to opposite ends of the cell just before it splits in two.

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Source: Gene Therapy Weekly (1997-09-22)

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