Published in Gene Therapy Weekly, September 29th, 1997
Numerous studies have explored HSV-TK suicide gene therapy in various cancer models, both in vitro and in vivo, using several different vectors and promoters. However, adenoviral-mediated HSV-TK/GCV suicide gene therapy has not been effectively addressed in the literature for human CNS malignancies.
In response to the need to find more effective therapies for CNS malignancies, Arnaud J.P.E. Vincent...
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