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Breast Cancer

Experimental Genetic Screening Probe Finds Overlooked Microscopic Cancers

Published in Gene Therapy Weekly, October 27th, 1997

Scientists are developing a genetic screening method that may be 10 to 100 times more sensitive than routine pathological analysis of lymph nodes for microscopic evidence of breast cancer.

If further testing proves that the method can identify women in whom breast cancer most likely will recur, it could help cancer treatment specialists decide whether or not to institute aggressive anti-cancer therapy on affected patients.

The screening method uses a polymerase chain reaction (PCR) probe that signals the presence or absence of up to four genes that have been associated with breast cancer. When the PCR probe finds any one of the genes in DNA from...

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