Cancer Therapies

Cancer Slowed When Blood Vessel Growth In Tumors Blocked

Published in Gene Therapy Weekly, November 3rd, 1997

Researchers at Duke University Medical Center have been able to significantly slow the growth of tumors on rats by preventing the tumors from "signaling" nearby blood vessels to shoot out capillaries to feed the cancer.

They did this by treating the tumors with an inhibitor designed to neutralize a protein, called Tie2, on tumor blood vessels. A single application of this potion slowed the growth of tumors by 75 percent, compared to animals with untreated tumors.

Charles Lin and his colleagues said their findings, published in the October 1997 issue of the Journal of Clinical Investigation, take them one step closer to a potential treatment for...

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Source: Gene Therapy Weekly (1997-11-03)

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