Conference Coverage (ICAAC)
New Mucosal Adjuvant Safe In Humans
Published in Gene Therapy Weekly, November 3rd, 1997
Tolerable dosages of the adjuvant, dubbed LTR192G , were well within the range expected to be used in combination with vaccine immunogens.
"This study demonstrated that LTR192G adjuvant can be safely given to adults at potentially adjuvant-active doses," said Michael Oplinger of the U.S. Army Medical Research Institute of Infectious Diseases (USAMRIID), Fort Detrick, Maryland.
LTR192G is a form of Escherichia coli heat-labile enterotoxin that has been genetically engineered to have extremely reduced toxicity...
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Source: Gene Therapy Weekly (1997-11-03)
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