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Cancer Vaccines (Conference News)

Modified Vaccinia Vector Shows Promise As Cancer Vaccine

Published in Gene Therapy Weekly, November 24th, 1997

In vitro results from using a replication deficient vaccinia virus, modified to express the human tyrosinase as a tumor associated antigen (TAA) as a cancer vaccine, are promising.

I. Drexler, representing colleagues from the Institute for Molecular Virology, the Technical University of Dresden, and the Johannes Gutenberg-University, Germany, presented results at the 3rd European Conference on Gene Therapy of Cancer, held September 11-13, 1997, in Berlin, Germany, suggesting that the modified vaccinia virus Ankara (MVA) might have a successful future as a cancer immunotherapeutic.

"The modified vaccinia virus Ankara, a highly attenuated vaccinia...

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