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Drug Resistance (Mycobacterium)

"Simultaneous Detection of Rifampin Conferring Mutations and Speciation of Clinical Isolates of Mycobacterium Using High Density Oligonucleotide Arrays."

Published in Gene Therapy Weekly, December 8th, 1997

According to an abstract submitted by the authors to the 37th ICAAC, held September 28 - October 1, 1997, in Toronto, Ontario, Canada, "Purpose: Using high density oligonucleotide arrays offers the possibility of examining large quantities of nucleotide sequence with a single hybridization. Applications of these arrays have thus far included: the sequence analysis of viral (1), mitochondrial (2) and human genomic sequences (3), as well as quantitative measurements of multiple murine gene expression (4) and functional mapping of the yeast genome (5). In this study we have sought to use both the genotyping information and the information provided in the form of the hybridization...

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