Drug Resistance

Gene Involved in Chloroquine Resistance Identified

Published in Gene Therapy Weekly, December 8th, 1997

Researchers in the November 28, 1997, issue of the journal Cell reported they had pinpointed a chunk of genetic material that makes the malaria parasite resistant to a primary drug used to fight the infection that afflicts 300 million people annually.

The research also confirms that resistance to the drug, chloroquine, developed independently in South America and Southeast Asia about 40 years ago.

About 300 million people worldwide are affected by malaria each year, according to the Cell article. Although it can be prevented by using drugs like chloroquine, the disease, transmitted by infected mosquitoes, remains an important threat to people who...

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Source: Gene Therapy Weekly (1997-12-08)

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