Published in Gene Therapy Weekly, December 15th, 1997
The studies provide in vivo evidence that people receiving highly active antiretroviral therapy (HAART) can regain most, but not all, lost immune function. They also suggest that stem-cell replacement, possibly incorporating anti-HIV gene therapies, could fully restore immune function.
"Hematopoietic microenvironments in HIV-1 infected individuals might remain functional to such an extent that immune reconstitution and stem cell gene therapeutic strategies for the treatment of AIDS may be feasible, provided that virus replication...
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