Cancer Gene Therapy
Cancer Phenotypes Reversed by Inhibition of PTI-1 Oncogene
Published in Gene Therapy Weekly, March 16th, 1998
Current diagnostic and prognostic prostate cancer strategies are limited by both sensitivity and specificity. There is an urgent need for both diagnostic and treatment strategies for this disease which is the second leading cause of cancer-related deaths in men.
Expression of the prostate tumor-inducing gene 1 (PTI-1) occurs both in human prostate, breast, colon and lung carcinoma cell lines and in patient-derived prostate carcinoma tissues, but not in normal prostate or benign hypertrophic prostate (BPH) tissues. It has also been detected in the serum of patients with...
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Source: Gene Therapy Weekly (1998-03-16)
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