Lung Transplantation
IL-10 Gene Transfer Inhibits Post-Transplant Fibrous Airway Obliteration
Published in Gene Therapy Weekly, April 6th, 1998
Bronchiolitis obliterans is a form of chronic allograft rejection characterized by progressive fibrous obliteration of the airways in lung transplant recipients. It is the leading cause of death and morbidity in lung transplantation cases. Once it starts, it ultimately results in death for the patient. There are currently no therapies against this fatal complication. Fifty percent of lung transplantation patients surviving their first three months develop this disorder.
IL-10 is an anti-inflammatory and...
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Source: Gene Therapy Weekly (1998-04-06)
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