Published in Gene Therapy Weekly, June 8th, 1998
An adeno-associated viral (AAV) gene delivery system was used to deliver human genes responsible for the production of L-dopa to the appropriate region of the brain, resulting in stable production of the enzyme responsible for L-dopa synthesis for one year, the duration of the study. The study was published by a team of scientists led by Ronald J. Mandel, Ph.D., in the June 1998 issue of the Journal of Neuroscience.
"The potential for gene...
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