Published in Gene Therapy Weekly, August 10th, 1998
Primitive hematopoietic progenitor cells (HPCs) are potential targets for the treatment of numerous hematopoietic diseases, by using retroviral-mediated gene transfer (RMGT). To achieve high efficiency of gene transfer into primitive HPCs, a delicate balance between cellular activation and proliferation and maintenance of hematopoietic potential must be established.
P. Veena and colleagues demonstrated that a subpopulation...
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