Antisense Therapy

Treatment Prevents Burkitt's Lymphoma In Mice

Published in Gene Therapy Weekly, September 21st, 1998

Researchers at Jefferson Medical College, Philadelphia, Pennsylvania, have used DNA therapy and the host immune system to stave off the development of cancer in mice.

Pharmacologist Eric Wickstrom, PhD, and research associate Janet B. Smith, PhD, have used antisense therapy to prevent the development of Burkitt's lymphoma in laboratory mice, showing that this protection is aided by the mouse's own immunity.

One of the limitations of effectively treating Burkitt's lymphoma with chemotherapy is that the drugs eventually wear off, explained Wickstrom, professor of microbiology and immunology and a member of Jefferson's Kimmel Cancer Center and the...

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Source: Gene Therapy Weekly (1998-09-21)

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