Combination Therapy
Immunological Factors Combine to Improve Gene Transfer into Marrow Cells
Published in Gene Therapy Weekly, October 12th, 1998
In order to increase gene transfer efficiencies into hematopoietic repopulating cells to bring them up to a level of clinical significance, Hans-Peter Kiem and colleagues from several Washington state institutions examined a number of culture and harvesting manipulations in a clinically relevant baboon model ("Improved Gene Transfer Into Baboon Marrow Repopulating Cells Using Recombinant Human Fibronectin Fragment CH-296 in Combination with Interleukin-6, Stem Cell Factor, FLT-3 Ligand, and Megakaryocyte Growth and Development Factor," Blood,...
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Source: Gene Therapy Weekly (1998-10-12)
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