Published in Gene Therapy Weekly, October 12th, 1998
In order to increase gene transfer efficiencies into hematopoietic repopulating cells to bring them up to a level of clinical significance, Hans-Peter Kiem and colleagues from several Washington state institutions examined a number of culture and harvesting manipulations in a clinically relevant baboon model ("Improved Gene Transfer Into Baboon Marrow Repopulating Cells Using Recombinant Human Fibronectin Fragment CH-296 in Combination with Interleukin-6, Stem Cell Factor, FLT-3 Ligand, and Megakaryocyte Growth and Development Factor," Blood,...
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