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Patent Issuance on Neurodegenerative Diseases Treatment Announced

Published in Gene Therapy Weekly, October 19th, 1998

NeoTherapeutics, Inc., Irvine, California, announced that the company has been issued a U.S. patent on gene regulation technology involved in treating neurodegenerative diseases.

The U.S. patent describes how purine derivatives, a class of drug compounds which includes Neotrofin (AIT-082, leteprinim potassium), can be used to selectively control "turning on or off of genes" for the protein molecules involved in nerve regeneration.

This patent represents a significant step forward in the treatment of neurodegenerative diseases utilizing a convenient oral medication to replace or augment the presence of neurotrophic factors in the brain and spinal...

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