Cancer Gene Therapy (Lung Cancer)

Scientists Suppress Tumor Growth in Animals, Aiming at Gene Therapy

Published in Gene Therapy Weekly, October 19th, 1998

Scientists at the Jefferson Medical College of Thomas Jefferson University in Philadelphia, Pennsylvania, believe they have taken the next step toward gene therapy trials for lung cancer.

They have demonstrated for the first time in laboratory animals that a normally protective anticancer gene, pRb2/p130, actually can block tumors from growing. A damaged version of the gene, termed a tumor suppressor, has been implicated in several cancers, including lung, breast, and endometrial.

Previous in vitro experiments had proven that tumors wouldn't grow when the gene and its protein product were present. But "curing cancer" in the test tube is one thing. ...

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Source: Gene Therapy Weekly (1998-10-19)

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