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Cancer Genetics

Scientists Find "Malignancy Gene"

Published in Gene Therapy Weekly, November 23rd, 1998

A "malignancy gene" found in breast, liver, colon, and other tumors but not in healthy tissue may offer a way to diagnose and treat cancer, scientists said.

The gene, which has been named "MAG" for malignancy-associated gene, actually may cause cancer to spread, according to Dr. Julia Ljubimova and colleagues at the Cedars-Sinai Medical Center in Los Angeles, California. The MAG gene was found in 90 percent of 51 tissue samples from premalignant and malignant tumors.

"We feel this gene may 'turn on' the process of malignancy," Ljubimova, who reported the findings in Cancer Research, said in a statement.

Her team is...

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