Antisense Technology
"Localization of a FITC-Labeled Phosphorothioate Oligodeoxynucleotide in the Skin After Topical Delivery by Iontophoresis and Electroporation."
Published in Gene Therapy Weekly, November 30th, 1998
According to the authors' abstract of an article published in Pharmaceutical Research, "Purpose: The aim of this study was to verify the hypothesis that the application of high voltage to the skin enhances both stratum corneum and keratinocyte permeability. Therefore, the transport of FITC-labeled phosphorothioate oligonucleotides (FITC-PS) administered by passive diffusion, iontophoresis, or electroporation was localized. Methods: Fluorescent microscopy and laser scanning confocal microscopy were used to visualize the FITC-PS transport at the tissue and cell level respectively in hairless rat skin after electroporation (5x(200V similar to 500 ms) or iontophoresis (same...
Want to see the full article?
We're a pay-per-view site for premium content. If you'd like to purchase this article, it's only $3.00.
Welcome to NewsRx!
Learn more about a six-week, no-risk free trial of Gene Therapy Weekly
Source: Gene Therapy Weekly (1998-11-30)
More Articles from Gene Therapy Weekly
- Gene Transfer
Efficiency Improved By Using Existing Methods - Cancer Gene Therapy
Gene Expression Determines Retinoid Sensitivity - Cancer Gene Therapy
Oral DNA Vaccination Provides Antitumor Immunity - Cancer Immunotherapy
Synthetic Lipopeptide Induces Tumoricidal Activity - Gene Transfer
Adenovirus-Mediated Gene Transfer Traumatizes the Brain - Gene Transfer
HIV Vectors Mediate High Efficiency Gene Transfer - More from this issue of Gene Therapy Weekly
NewsRx is Social
Follow us on your favorite social network by clicking on a button below:
Top Medical Newsletters
Awards
Best Health/Healthcare Content, 2012
Best Health/Healthcare Content, 2011
Best e-Business Site, 2010
Best e-Business Site, 2009
Best e-Business Site, 2008
Best e-Business Site, 2007
Best e-Business Site, 2006
Best Healthcare Content, 2005
Best Overall Internet Site, 2005
Best Interactive Site, 2005
Facts & Stats
NewsRx also is available at LexisNexis, Gale, ProQuest, Factiva, Dialog, Thomson Reuters, NewsEdge, and Dow Jones.
- Google 2010 PageRank: #2 Among Top Health News and Media Publications
- Google 2010 PageRank: #2 Among Top Science Publications in Biology/Physiology
- Google 2010 PageRank: #2 Among Top News and Media for the Business of Pharmaceuticals
- Amazon's Alexa 2010 PageRank: #2 News and Media Site for the Pharmaceutical Industry
