Pain Management
"Adenoviral Expression of a-Endorphin in Cell Cultures."
Published in Gene Therapy Weekly, November 30th, 1998
According to an abstract submitted by the author to the Annual Meeting of the American Society of Anesthesiologists, held October 18-20, 1998, in Orlando, Florida, "Introduction: Gene therapy may offer an alternative for treatment of the severe, intractable pain often accompanying the terminal stages of cancer. A replication-defective adenovirus containing the gene expressing b-endorphin was made (AdNGFbEND). The present study was designed to test that cultured cells transduced with the virus would express extracellular b-endorphin. Methods: Bovine smooth muscle cells (AG08595A, Coriel Institute, Camden, NJ) were grown to confluence in 12 well plates (culture media 1.0...
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Source: Gene Therapy Weekly (1998-11-30)
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