Gene Delivery

Novel Vectors Represent New Family of Gene Transfer Vehicles

Published in Gene Therapy Weekly, December 7th, 1998

Cationic lipid vectors derived from glycine betaine represent a new family of gene transfer vehicles.

V. Floch and colleagues from the University Hospital, Etsbo, Brest, France, developed efficient new agents for the transfection of eukaryotic cells ("New Biocompatible Cationic Amphiphiles Derivative from Glycine Betaine: A Novel Family of Efficient Nonviral Gene Transfer Agents," Biochemical and Biophysical Research Communications, October 9, 1998;251(1):360-365).

"In this study we present three novel molecules differing by the length of their aliphatic chains (R=12, R=14, R=16)," wrote Floch et al. "The lyotropic properties of these cationic...

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Source: Gene Therapy Weekly (1998-12-07)

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