Septic Shock

Septic Shock Protein Finding May Lead to Genetic Test

Published in Gene Therapy Weekly, December 28th, 1998

A team of Howard Hughes Medical Institutes (HHMI) researchers and their colleagues have discovered that malfunctions in a protein required for maintaining the body's early-warning system for virulent bacterial infections set the stage for septic shock.

Septic shock kills some 20,000 people in the United States and 1 million people worldwide each year. According to Bruce Beutler, an HHMI investigator at the University of Texas Southwestern Medical Center at Dallas, the finding could lead to a genetic test to identify people who might be more susceptible to septic shock. Identifying such individuals in advance would allow physicians to treat patients preemptively with...

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Source: Gene Therapy Weekly (1998-12-28)

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