Carcinogenesis
HBV pX Gene Linked to Liver Cancer
Published in Gene Therapy Weekly, February 1st, 1999
C. Tarn and colleagues report construction and characterization of tetracycline-controlled hepatitis B virus pX-expressing hepatocyte (AML12) cell lines.
"These cell lines were constructed in AML12 clonal isolates (clones 3 and 4), which express constitutively the tetracycline-controlled transactivator," Tarn et al. wrote ("Differential Immediate Early Gene Expression in Conditional Hepatitis B Virus pX-Transforming Versus Nontransforming Hepatocyte Cell Lines," J Biol Chem, January 1999;274(4):2327-2336).
Since pX is...
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Source: Gene Therapy Weekly (1999-02-01)
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