DNA Vaccines
"Antibody Responses to Single and Multiple Brugia malayi Antigens After DNA Vaccination by I.M. Injection or Gene Gun in Mice."
Published in Gene Therapy Weekly, February 15th, 1999
According to an abstract submitted by the authors to the 4th International Meeting of Tropical Medicine and Parasitology, held October 8-10, 1998, in Guilin, China, "We have previously reported that mice develop humoral and cellular immune responses to filarial antigens after i.m. injection of plasmid DNA encoding B. malayi antigens. In the present study, murine antibody responses were studied after DNA vaccination by i.m. injection (IM) or by injection of DNA coated gold particles with the Helios Gene Gun (HGG). Mice were immunized twice with either 50 (mu)g per antigen of plasmid DNA (for IM) or 5 (mu)g DNA per antigen (for HGG) with plasmids encoding either a single B....
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Source: Gene Therapy Weekly (1999-02-15)
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