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Virology

Viral Gateway into Cells Could Play Role in Diagnosis and Treatment of Diseases

Published in Gene Therapy Weekly, February 15th, 1999

Viruses change identities frequently and find secret gateways, known as receptors, through cell walls.

Now, Chetankumar Tailor, PhD, and David Kabat, PhD, both of Oregon Health Sciences University, have uncloaked a mechanism used by certain leukemia viruses to attach themselves to a cell surface and then sneak into the cell's interior.

The same researchers have devised a way to rapidly clone human genes that encode receptors for selected viruses. Their study results, published in the February 1999 issue of the Proceedings of the National Academy of Sciences, could help uncover clues to the diagnosis and treatment of not only leukemia, but HIV and...

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