Published in Gene Therapy Weekly, March 1st, 1999
F. Galbiati and colleagues from the Albert Einstein College of Medicine, New York, investigated the effect that downregulation of caveolin-1 has on tumorigenicity.
"Caveolin-1 is a principal component of caveolae membranes in vivo," wrote Galbiati et al. "Caveolin-1 mRNA and protein expression are lost or reduced during cell transformation by activated oncogenes."
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