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Prostate Cancer

Common Cancer - A Different Process Altogether?

Published in Gene Therapy Weekly, March 8th, 1999

Nearly 90 percent of prostate cancers - "the typical, garden varieties," according to Johns Hopkins scientists - are linked to a previously unsuspected but common genetic process that could be reversible.

The process looks to be a fundamental one in cancer and appears in other common forms of the disease, like breast cancer.

Unlike cancers due to mutations that make structural changes in a gene, such as the colon cancers that run in families, most prostate cancer may involve a process called "gene switching," the researchers said. Switching occurs when certain members of a family of genes are switched on while others in the family shut down. ...

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