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Worm Enzyme Helps Clarifies Role of Oxidative Damage

Published in Gene Therapy Weekly, May 31st, 1999

A cell-protecting enzyme needed for long life in worms may help in finding better treatments for Alzheimer's and other human diseases associated with aging, scientists said.

The finding of the enzyme reported in the May 13, 1999, issue of Nature "gets us closer to understanding what's involved in the aging process and where we can intervene," said Anna McCormick, U.S. National Institute on Aging.

Researchers led by biologist Martin Chalfie at Columbia University, New York, studied a nearly microscopic roundworm known as Caenorhabditis elegans. When it is well fed, it survives only about three weeks, but it can withstand food shortages...

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