Animal Models
System Permits Study of Rh Function and Structure
Published in Gene Therapy Weekly, June 14th, 1999
The Rh blood group system is of clinical importance in blood transfusion and as the cause of hemolytic disease of the newborn. Other than their role as carriers of Rh antigens, very little is known about the function of the Rh polypeptides.
C.M. Westhoff and colleagues, University of Pennsylvania School of Medicine characterized the Rh homologue from Mus musculus, as a first step to generate an animal model system in which to study the structure and function of Rh, and to extend the phylogenetic analysis of RH...
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Source: Gene Therapy Weekly (1999-06-14)
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