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Patents Issued for Technologies that Destroy Cancer Tumors

Published in Gene Therapy Weekly, July 12th, 1999

Calydon, Inc., Sunnyvale, California, announced the issuance of two patents that expand its intellectual property in the area of engineering viruses to replicate in and kill prostate cancer cells.

One U.S. patent claims a modified adenovirus that may be used as a therapeutic to introduce genetic constructs that are toxic to prostate cancer cells in a highly targeted and specific manner. The other patent claims a human prostate-specific transcriptional regulatory sequence, the polynucleotides that comprise such regions, the toxin gene that is controlled by the regulatory sequence, and methods for treating prostate disease using toxin gene constructs.

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