Published in Gene Therapy Weekly, July 12th, 1999
E. Dodds and colleagues from the University of London Royal Holloway and Bedford New College, England, investigated methods of improving adenovirus infection in cultured myotubes ("Cationic Lipids and Polymers are Able to Enhance Adenoviral Infection of Cultured Mouse Myotubes," Journal of Neurochemistry, May 1999;72(5):2105-2112).
Past research has demonstrated that adenovirus-mediated gene transfer can be used to promote efficient expression of various reporter and therapeutic transgenes such as minidystrophin in skeletal muscle tissue. However,...
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