Cancer Gene Therapy
Bax Gene Transfer Eradicates Ovarian Cancer Cells
Published in Gene Therapy Weekly, July 26th, 1999
Y.T. Tai and colleagues from Harvard University School of Medicine explored a gene therapy anticancer strategy based on the BAX proapoptotic protein ("In Vivo Cytotoxicity of Ovarian Cancer Cells Through Tumor-Selective Expression of the Bax Gene," Cancer Research, May 1, 1999;59(9):2121-2126).
Research has demonstrated that the BAX protein induces cell death either directly, through its effects on mitochondrial function, or indirectly, by lowering the apoptotic threshold in response to certain chemotherapy agents.
...
Want to see the full article?
We're a pay-per-view site for premium content. If you'd like to purchase this article, it's only $3.00.
Welcome to NewsRx!
Learn more about a six-week, no-risk free trial of Gene Therapy Weekly
Source: Gene Therapy Weekly (1999-07-26)
More Articles from Gene Therapy Weekly
- Conference Coverage (ASCO)
Study Checks for Horizontal Transmission of Ad Vector - Antisense Therapy
Oligonucleotides Are Effective for Ocular Gene Therapy - Vector Development
DC-Chol/DOPE Liposomes are Good Non-Viral Vectors - Vector Research
Foamy Virus Undergoes Scrutiny in Its Natural Environment - AIDS Therapies
2 Against 1 - CNS Disease
Transplanted Neural Stem Cells May Be Useful - More from this issue of Gene Therapy Weekly
NewsRx is Social
Follow us on your favorite social network by clicking on a button below:
Top Medical Newsletters
Awards
Best Health/Healthcare Content, 2012
Best Health/Healthcare Content, 2011
Best e-Business Site, 2010
Best e-Business Site, 2009
Best e-Business Site, 2008
Best e-Business Site, 2007
Best e-Business Site, 2006
Best Healthcare Content, 2005
Best Overall Internet Site, 2005
Best Interactive Site, 2005
Facts & Stats
NewsRx also is available at LexisNexis, Gale, ProQuest, Factiva, Dialog, Thomson Reuters, NewsEdge, and Dow Jones.
- Google 2010 PageRank: #2 Among Top Health News and Media Publications
- Google 2010 PageRank: #2 Among Top Science Publications in Biology/Physiology
- Google 2010 PageRank: #2 Among Top News and Media for the Business of Pharmaceuticals
- Amazon's Alexa 2010 PageRank: #2 News and Media Site for the Pharmaceutical Industry
