Published in Gene Therapy Weekly, September 20th, 1999
M. Tao and colleagues from the Chiba Institute of Technology, Japan, investigated antisense phosphodiester (ODNs) and phosphorothioate (S-ODNs) oligonucleotides for their abilities to inhibit telomerase activity in the HeLa cell line. Their study results were reported in the journal FEBS Letters ("Specific Inhibition of Human Telomerase Activity by Transfection Reagent, FuGENE6-Antisense Phosphorothioate Oligonucleotide Complex in HeLa Cells," FEBS Letters, 1999;454(3):312-316).
"Human telomerase might...
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