Vector Development

Use of a Transfection Reagent Improves Gene Transfer

Published in Gene Therapy Weekly, September 20th, 1999

The transfection reagent, FuGENE6-antisense phosphorothioate oligonucleotide complex, specifically inhibits human telomerase activity in HeLa cells.

M. Tao and colleagues from the Chiba Institute of Technology, Japan, investigated antisense phosphodiester (ODNs) and phosphorothioate (S-ODNs) oligonucleotides for their abilities to inhibit telomerase activity in the HeLa cell line. Their study results were reported in the journal FEBS Letters ("Specific Inhibition of Human Telomerase Activity by Transfection Reagent, FuGENE6-Antisense Phosphorothioate Oligonucleotide Complex in HeLa Cells," FEBS Letters, 1999;454(3):312-316).

"Human telomerase might...

Want to see the full article?

Purchase this article for only $3.00

We're a pay-per-view site for premium content. If you'd like to purchase this article, it's only $3.00.

Welcome to NewsRx!

Learn more about a six-week, no-risk free trial of Gene Therapy Weekly

Source: Gene Therapy Weekly (1999-09-20)

NewsRx is Social

Top Medical Newsletters

Awards

Best Health/Healthcare Content, 2012
Best Health/Healthcare Content, 2011
Best e-Business Site, 2010
Best e-Business Site, 2009
Best e-Business Site, 2008
Best e-Business Site, 2007
Best e-Business Site, 2006
Best Healthcare Content, 2005
Best Overall Internet Site, 2005
Best Interactive Site, 2005

Facts & Stats

NewsRx also is available at LexisNexis, Gale, ProQuest, Factiva, Dialog, Thomson Reuters, NewsEdge, and Dow Jones.

Google 2010 PageRank: #2 Among Top Health News and Media Publications
Google 2010 PageRank: #2 Among Top Science Publications in Biology/Physiology
Google 2010 PageRank: #2 Among Top News and Media for the Business of Pharmaceuticals
Amazon's Alexa 2010 PageRank: #2 News and Media Site for the Pharmaceutical Industry